Article
Mechanisms of drug resistance: daptomycin resistance.
Annals of the New York Academy of Sciences - 1 Sept 2015
Tran Truc T, Munita Jose M, Arias Cesar A
Abstract excerpt
Daptomycin (DAP) is a cyclic lipopeptide with in vitro activity against a variety of Gram-positive pathogens, including multidrug-resistant organisms. Since its introduction into clinical practice in 2003, DAP has become an important key frontline antibiotic for severe or deep-seated infections caused by Gram-positive organisms. Unfortunately, DAP resistance (DAP-R) has been extensively documented in clinically...
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