Article
Identification and characterisation of a novel mechanism of antibiotic resistance
2018-01-01
Abstract excerpt
Daptomycin is a bactericidal antibiotic of last resort for serious infections caused by methicillin-resistant Staphylococcus aureus (MRSA). Although resistance is rare, treatment failure can occur in >20% of cases and so there is a pressing need to identify and mitigate factors that contribute to poor therapeutic outcomes. Work described in this thesis revealed that loss of the Agr quorum-sensing system, which fre...
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Identifiers and source
- Literature Corpus work
- f842dca9-407c-5611-aed9-272500b1b7e4
- DOI
- 10.25560/56613