Article
The Cysteine-rich Domain of the DHHC3 Palmitoyltransferase Is Palmitoylated and Contains Tightly Bound Zinc.
The Journal of biological chemistry - 4 Dec 2015
Gottlieb Colin D, Zhang Sheng, Linder Maurine E
Abstract excerpt
DHHC palmitoyltransferases catalyze the addition of the fatty acid palmitate to proteins on the cytoplasmic leaflet of cell membranes. There are 23 members of the highly diverse mammalian DHHC protein family, all of which contain a conserved catalytic domain called the cysteine-rich domain (CRD). DHHC proteins transfer palmitate via a two-step catalytic mechanism in which the enzyme first modifies itself with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.