Article
A systematic analysis of protein palmitoylation in Caenorhabditis elegans.
BMC genomics - 2 Oct 2014
Edmonds Matthew J, Morgan Alan
Abstract excerpt
BACKGROUND: Palmitoylation is a reversible post-translational protein modification which involves the addition of palmitate to cysteine residues. Palmitoylation is catalysed by the DHHC family of palmitoyl-acyl transferases (PATs) and reversibility is conferred by palmitoyl-protein thioesterases (PPTs). Mutations in genes encoding both classes of enzymes are associated with human diseases, notably neurological...
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