Association of haplotypes of the TLR8 locus with susceptibility to Crohn's and Behçet's diseases.

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Article

Association of haplotypes of the TLR8 locus with susceptibility to Crohn's and Behçet's diseases.

Clinical and experimental rheumatology - 1 Jan 2000

Ortiz-Fernández Lourdes, García-Lozano José-Raúl, Montes-Cano Marco-Antonio, Conde-Jaldón Marta, Leo Eduardo, Ortego-Centeno Norberto, Gómez-García María, García-Hernández Francisco-José, Márquez José-Luis, Espinosa Gerard, Graña-Gil Genaro, Sánchez-Bursón Juan, Juliá María-Rosa, Blanco Ricardo, Barnosi-Marín Ana-Celia, Solans Roser, Fanlo Patricia, Rodríguez-Carballeira Mónica, Camps Teresa, Castañeda Santos, Martín Javier, González-Escribano María-Francisca

Abstract excerpt

OBJECTIVES: The aim of this study was to investigate the role of the TLR8, a mediator of innate inflammatory response, in susceptibility to two immune-mediated disorders characterised by dysregulation of the immune response, Crohn's and Behçet's diseases (CD and BD). METHODS: A total of 844 CD, 371 BD patients and 1385 controls were genotyped in 8 tag single nucleotide polymorphisms (tSNPs) in the locus TLR8...

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PMID: 26486764

Genes

TLR8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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