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Article

Association of Toll-like receptor 10 and susceptibility to Crohn's disease independent of NOD2.

Genes and immunity - 1 Dec 2011

Abad C, González-Escribano M F, Diaz-Gallo L M, Lucena-Soto J M, Márquez J L, Leo E, Crivell C, Gómez-García M, Martín J, Núñez-Roldán A, García-Lozano J R

Abstract excerpt

Impaired innate inflammatory response has a key role in the Crohn's disease (CD) pathogenesis. The aim of this study was to investigate the possible role of the TLR10-TLR1-TLR6 gene cluster in CD susceptibility. A total of 508 CD patients (284, cohort 1 and 224, cohort 2) and 576 controls were included. TLR10-TLR1-TLR6 cluster single-nucleotide polymorphisms genotyping, NOD2 mutations and TLR10 mRNA...

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Source

Identifiers

PMID: 21716313
DOI: 10.1038/gene.2011.41

Genes

TLR10
NOD2
TLR1
TLR6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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