Article
Toll-like receptor 4 (TLR4) gene polymorphisms in Italian patients with Behçet's disease.
Clinical and experimental rheumatology - 1 Jan 2000
Boiardi L, Atzeni F, Casali B, Farnetti E, Nicoli D, Pipitone N, Catanoso M G, Olivieri I, Cantini F, Salvi F, La Corte R, Triolo G, Filippini D, Paolazzi G, Salvarani C
Abstract excerpt
OBJECTIVE: To investigate potential associations between toll-like receptor 4 (TLR4) gene polymorphisms and susceptibility to, clinical features, and severity of Behçet's disease (BD). METHODS: A total of 189 Italian patients who satisfied the International Study Group criteria for BD and 210 healthy age- and sex-matched blood donors were genotyped for two coding single nucleotide polymorphisms of TLR4 (Asp299Gly...
Topics
- Adult
- Behcet Syndrome
- Case-Control Studies
- Female
- Genotype
- Humans
- Italy
- Male
- Middle Aged
- Polymorphism, Single Nucleotide
- Severity of Illness Index