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Detection of germline variants using expanded multigene panels in patients with localized pancreatic cancer.

HPB : the official journal of the International Hepato Pancreato Biliary Association - 1 Dec 2020

Krepline Ashley N, Geurts Jennifer L, Akinola Idayat, Christians Kathleen K, Clarke Callisia N, George Ben, Ritch Paul S, Khan Abdul H, Hall William A, Erickson Beth A, Griffin Mike O, Evans Douglas B, Tsai Susan

Abstract excerpt

BACKGROUND: Current guidelines recommend genetic testing for all patients with pancreatic cancer (PC). METHODS: Patients with localized PC who received neoadjuvant therapy between 2009 and 2018 were identified. Genetic consultation (including personal and family history of cancer), genetic testing, and variant data were abstracted. RESULTS: Of 510 patients identified, 163 (32%) underwent genetic counseling and...

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Genetic Predisposition to Disease
Genetic Testing
Germ Cells
Germ-Line Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pancreatic Neoplasms

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PMID: 32354656
DOI: 10.1016/j.hpb.2020.03.022

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