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Article

Association of APOE with tau-tangle pathology with and without β-amyloid.

Neurobiology of aging - 1 Jan 2016

Farfel Jose M, Yu Lei, De Jager Philip L, Schneider Julie A, Bennett David A

Abstract excerpt

This study tested the hypothesis that the association of apolipoprotein E (APOE) with paired helical filament tau (PHF-tau) tangle pathology differs in brains with and without β-amyloid. Participants were 1056 autopsied individuals from 2 clinical-pathologic cohort studies of aging and Alzheimer's disease (AD), the Religious Orders Study, and the Rush Memory and Aging Project. Neuropathologic measures were...

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Identifiers

PMID: 26481403
DOI: 10.1016/j.neurobiolaging.2015.09.011
PMCID: PMC4716785

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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