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Article

The renal microenvironment modifies dendritic cell phenotype.

Kidney international - 1 Jan 2016

Chessa Federica, Mathow Daniel, Wang Shijun, Hielscher Thomas, Atzberger Ann, Porubsky Stefan, Gretz Norbert, Burgdorf Sven, Gröne Hermann-Josef, Popovic Zoran V

Abstract excerpt

Renal dendritic cells are a major component of the renal mononuclear phagocytic system. In the renal interstitium, these cells are exposed to an osmotic gradient, mainly sodium, whose concentration progressively increases towards inner medulla. Renal allograft rejection affects predominantly the cortex, suggesting a protective role of the renal medullary micromilieu. Whether osmolar variations can modulate the...

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PMID: 26466317
DOI: 10.1038/ki.2015.292

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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