Article
Pharmacological manipulation of dendritic cells in the pursuit of transplantation tolerance.
Current opinion in organ transplantation - 1 Aug 2011
Leishman Alison J, Silk Kathryn M, Fairchild Paul J
Abstract excerpt
PURPOSE OF REVIEW: Although long-term immune suppression remains the intervention of choice for the treatment of allograft rejection, transplantation tolerance would achieve graft survival with fewer inherent risks. Although the use of dendritic cells for the induction of tolerance might confer antigen specificity, factors determining the balance between tolerogenicity and immunogenicity remain uncertain, as does...
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