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Characterization of T cell repertoire of blood, tumor, and ascites in ovarian cancer patients using next generation sequencing

27 May 2015

Abstract excerpt

Tumor-infiltrating lymphocytes (TILs) play an important role in regulating the host immune response and are one of key factors in defining tumor microenvironment. Some studies have indicated that T cell infiltration in malignant ascites is associated with clinical outcome, but few studies have performed detailed characterization of T cell diversity or clonality in malignant effusions. We have applied a next...

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PMID: 26451311
DOI: 10.1080/2162402x.2015.1030561

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