Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prediction of CD8+ T cell infiltration in the tumor microenvironment of HGSOC patients

20 Aug 2025

Abstract excerpt

The tumor microenvironment (TME), particularly CD8 + T cell infiltration, critically influences high-grade serous ovarian cancer (HGSOC) progression and treatment response. The development and management of cancer depend heavily on CD8 + T cells. Identifying non-invasive predictors of TME immune status is crucial. We investigated whether clinicopathologic characteristics and peripheral blood parameters could...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to Lymphoma Diagnosis and Treatment
Share to Renal cell carcinoma treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40836058
DOI: 10.1038/s41598-025-14720-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prediction of CD8+ T cell infiltration in the tumor microenvironment of HGSOC patientsPMID 40836058Read ↗

A Nine-Immune-Related Gene Prognostic Signature for Predicting Outcomes in High-Grade Serous Ovarian CancerSemantic proximity Read ↗

Development a prognostic risk model based on B cell-related immune genes in Ovarian Cancer by integrative analysis of single-cell and bulk RNA sequencing dataSemantic proximity Read ↗

A Risk Model Based on Tumor Microenvironment to Predict Survival and Immunotherapy Efficacy for Ovarian CancerSemantic proximity Read ↗

UBE2J1 is identified as a novel plasma cell-related gene involved in the prognosis of high-grade serous ovarian cancerSemantic proximity Read ↗

Preliminary Exploration of the Relationship between Tumor Microenvironment in Malignant Ascites and Patient PrognosisSemantic proximity Read ↗

Unraveling tumor-immune heterogeneity in advanced ovarian cancer uncovers immunogenic effect of chemotherapy.Semantic proximity Read ↗

APOBEC3G Expression Correlates with T-Cell Infiltration and Improved Clinical Outcomes in High-grade Serous Ovarian CarcinomaSemantic proximity Read ↗

Analyzing the extracellular matrix-dominated immune landscape of high-grade serous ovarian cancer to determine prognosis and guide therapySemantic proximity Read ↗

New immune phenotypes for treatment response in high-grade serous ovarian carcinoma patients.Semantic proximity Read ↗

Subtype-specific analysis of gene co-expression networks and immune cell profiling reveals high grade serous ovarian cancer subtype linkage to variable immune microenvironmentSemantic proximity Read ↗

Construction of the Novel Immune Risk Scoring System Related to CD8 + T Cells in Uterine Corpus Endometrial CarcinomaSemantic proximity Read ↗

The Prognostic Significance of Tumor-Infiltrating Lymphocytes, PD-L1, BRCA Mutation Status and Tumor Mutational Burden in Early-Stage High-Grade Serous Ovarian Carcinoma-A Study by the Spanish Group for Ovarian Cancer Research (GEICO).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.