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Article

BRAF Testing in Multifocal Papillary Thyroid Carcinoma.

BioMed research international - 1 Jan 2015

Kimbrell Hillary Z, Sholl Andrew B, Ratnayaka Swarnamala, Japa Shanker, Lacey Michelle, Carpio Gandahari, Bhatia Parisha, Kandil Emad

Abstract excerpt

BACKGROUND: BRAF V600E mutation is associated with poor prognosis in patients with papillary thyroid carcinoma (PTC). PTC is often multifocal, and there are no guidelines on how many tumors to test for BRAF mutation in multifocal PTC. METHODS: Fifty-seven separate formalin-fixed and paraffin-embedded PTCs from twenty-seven patients were manually macrodissected and tested for BRAF mutation using a commercial...

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Identifiers

PMID: 26448939
DOI: 10.1155/2015/486391
PMCID: PMC4584030

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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