Article
Mutational patterns and novel mutations of the BRAF gene in a large cohort of Korean patients with papillary thyroid carcinoma.
Thyroid : official journal of the American Thyroid Association - 1 Aug 2012
Jung Chan-Kwon, Im So-Young, Kang Yeo-Ju, Lee Hyoungnam, Jung Eun-Sun, Kang Chang-Suk, Bae Ja-Seong, Choi Yeong-Jin
Abstract excerpt
BACKGROUND: BRAF mutation is the most common genetic event in papillary thyroid carcinoma (PTC); however, the prevalence and patterns of the mutation vary worldwide. We investigated the frequency and type of BRAF mutations based on the histologic subtypes in a large cohort of Korean patients with PTC. METHODS: A total of 1041 consecutive PTCs were classified according to histologic subtypes. BRAF mutations were...
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