Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Subclonality for BRAF Mutation in Papillary Thyroid Carcinoma Is Associated With Earlier Disease Stage.

The Journal of clinical endocrinology and metabolism - 1 Apr 2016

Finkel Alona, Liba Lior, Simon Einav, Bick Tova, Prinz Elad, Sabo Edmond, Ben-Izhak Ofer, Hershkovitz Dov

Abstract excerpt

CONTEXT: The presence of driver mutations only in a subset of tumor cells within a single lesion, defined as subclonality, is being appreciated as a clinically significant factor. BRAF mutation is the most common driver mutation in papillary thyroid carcinoma (PTC). There are conflicting data in the literature regarding the presence of BRAF mutation subclonality in PTC and its clinical significance. OBJECTIVE:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Carcinoma, Papillary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Follow-Up Studies

Share to High-Throughput Nucleotide Sequencing

Share to Lymphatic Metastasis

Share to Neoplasm Staging

Share to Proto-Oncogene Proteins B-raf

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 26835544
DOI: 10.1210/jc.2015-4031

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Subclonality for BRAF Mutation in Papillary Thyroid Carcinoma Is Associated With Earlier Disease Stage.PMID 26835544Read ↗

Different structural components of conventional papillary thyroid carcinoma display mostly identical BRAF status.Semantic proximity Read ↗

BRAF V600E Mutations in Papillary Thyroid Carcinoma: Their Relation to Clinical Features and Oncologic Outcomes in A Single Cancer Centre ExperienceSemantic proximity Read ↗

BRAF<sup>V600E</sup> Mutation is Associated with Tumor Aggressiveness in Papillary Thyroid CancerSemantic proximity Read ↗

Clinical significance of BRAF mutation in thyroid papillary cancer.Semantic proximity Read ↗

BRAF(V⁶⁰⁰E) mutation and its association with clinicopathological features of papillary thyroid microcarcinoma: A meta-analysis.Semantic proximity Read ↗

Higher rate of BRAF mutation in papillary thyroid cancer over time: a single-institution study.Semantic proximity Read ↗

Immunohistochemical detection of mutated BRAF V600E supports the clonal origin of BRAF-induced thyroid cancers along the spectrum of disease progression.Semantic proximity Read ↗

Clinicopathologic significance of BRAF V600E mutation in papillary carcinomas of the thyroid: a meta-analysis.Semantic proximity Read ↗

Prevalence and Clinicopathological Significance of BRAF V600E Mutation in Papillary Thyroid Carcinoma: A Retrospective Cohort Study from Kerala, IndiaSemantic proximity Read ↗

Geographical mapping of a multifocal thyroid tumour using genetic alteration analysis & miRNA profiling.Semantic proximity Read ↗

Most multifocal papillary thyroid carcinomas acquire genetic and morphotype diversity through subclonal evolution following the intra-glandular spread of the initial neoplastic clone.Semantic proximity Read ↗

Clonality analysis of multifocal papillary thyroid carcinoma by using genetic profilesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.