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Article

Analysis of differential BRAF(V600E) mutational status in multifocal papillary thyroid carcinoma: evidence of independent clonal origin in distinct tumor foci.

Cancer - 15 Oct 2006

Park So Yeon, Park Young Joo, Lee Yu Jin, Lee Hyun Sook, Choi Sung Hee, Choe Gheeyoung, Jang Hak-Chul, Park Seong Hoe, Park Do Joon, Cho Bo Youn

Abstract excerpt

BACKGROUND: Papillary thyroid cancers often occur as multiple foci. Multifocal cancers have been considered to have a poor prognosis because they are thought to be the consequence of intrathyroidal spread of the papillary cancer. However, to the authors' knowledge there has been little investigation into whether multifocal thyroid papillary carcinomas arise from the intrathyroidal spread of a single carcinoma or...

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Share to Carcinoma, Papillary
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to BRAF gene

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Share to Neoplasms, Multiple Primary

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Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 16983703
DOI: 10.1002/cncr.22218

Genes

BRAF

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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