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Article

Utilization of a MAB for BRAF(V600E) detection in papillary thyroid carcinoma.

Endocrine-related cancer - 1 Dec 2012

Bullock M, O'Neill C, Chou A, Clarkson A, Dodds T, Toon C, Sywak M, Sidhu S B, Delbridge L W, Robinson B G, Learoyd D L, Capper D, von Deimling A, Clifton-Bligh R J, Gill A J

Abstract excerpt

Identification of BRAF(V600E) in thyroid neoplasia may be useful because it is specific for malignancy, connotes a worse prognosis, and is the target of novel therapies currently under investigation. Sanger sequencing is the 'gold standard' for mutation detection but is subject to sampling error...

Topics

Antibodies, Monoclonal
Carcinoma
Carcinoma, Papillary
DNA, Neoplasm
Humans
Immunohistochemistry
Mutation
Polymerase Chain Reaction
Proto-Oncogene Proteins B-raf
Sequence Analysis, DNA
Thyroid Cancer, Papillary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Thyroid Neoplasms

Tissue Embedding

Source

Identifiers

PMID: 22997209
DOI: 10.1530/ERC-12-0239

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-22997209-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Utilization of a MAB for BRAF(V600E) detection in papillary thyroid carcinoma.PMID 22997209Read ↗

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Detection of BRAF mutation in thyroid papillary carcinomas by mutant allele-specific PCR amplification (MASA).Semantic proximity Read ↗

Clinical Implication of Highly Sensitive Detection of the BRAF V600E Mutation in Fine-Needle Aspirations of Thyroid Nodules: A Comparative Analysis of Three Molecular Assays in 4585 Consecutive Cases in a BRAF V600E Mutation-Prevalent AreaSemantic proximity Read ↗

Comparison of Immunohistochemistry and Direct Sequencing Methods for Identification of the BRAFV600E Mutation in Papillary Thyroid Carcinoma.Semantic proximity Read ↗

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Detection of BRAF Mutation on Fine Needle Aspiration Biopsy Specimens: A New Diagnostic Tool for Papillary Thyroid CancerSemantic proximity Read ↗

Unveiling a rare BRAF mutation in minimally invasive follicular thyroid carcinoma: A case report.Semantic proximity Read ↗

Role of BRAF molecular analysis in the management of papillary thyroid carcinoma: analysis of cytological and histological samples.Semantic proximity Read ↗

Immunohistochemical detection of mutated BRAF V600E supports the clonal origin of BRAF-induced thyroid cancers along the spectrum of disease progression.Semantic proximity Read ↗

Diagnostic Value of Immunohistochemistry for the Detection of the <i> BRAF <sup>V600E</sup> </i> Mutation in Papillary Thyroid Carcinoma: Comparative Analysis with Three DNA-Based AssaysSemantic proximity Read ↗

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