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Article

Molecular and histopathologic characteristics of multifocal papillary thyroid carcinoma.

The American journal of surgical pathology - 1 Oct 2013

Bansal Mona, Gandhi Manoj, Ferris Robert L, Nikiforova Marina N, Yip Linwah, Carty Sally E, Nikiforov Yuri E

Abstract excerpt

Papillary thyroid carcinoma (PTC) is frequently multifocal, which can represent either intraglandular spread from a single primary tumor or multiple synchronous primary tumors (MSPTs). To distinguish and characterize these entities, we investigated whether multifocal PTCs contain genetically similar or different mutations and have particular histopathologic characteristics. In 60 cases of PTC with 2 to 4 discrete...

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Source

Identifiers

PMID: 23797723
DOI: 10.1097/PAS.0b013e318292b780

Genes

RET
BRAF
HRAS
KRAS
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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