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Article

Hypoxia Induces Epithelial-Mesenchymal Transition in Follicular Thyroid Cancer: Involvement of Regulation of Twist by Hypoxia Inducible Factor-1α.

Yonsei medical journal - 1 Nov 2015

Yang Yeon Ju, Na Hwi Jung, Suh Michelle J, Ban Myung Jin, Byeon Hyung Kwon, Kim Won Shik, Kim Jae Wook, Choi Eun Chang, Kwon Hyeong Ju, Chang Jae Won, Koh Yoon Woo

Abstract excerpt

PURPOSE: Although follicular thyroid cancer (FTC) has a relatively fair prognosis, distant metastasis sometimes results in poor prognosis and survival. There is little understanding of the mechanisms contributing to the aggressiveness potential of thyroid cancer. We showed that hypoxia inducible factor-1α (HIF-1α) induced aggressiveness in FTC cells and identified the underlying mechanism of the HIF-1α-induced...

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Source

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Identifiers

PMID: 26446630
DOI: 10.3349/ymj.2015.56.6.1503
PMCID: PMC4630036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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