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Trop2 enhances invasion of thyroid cancer by inducing MMP2 through ERK and JNK pathways

14 Jul 2017

Abstract excerpt

BACKGROUND: Mounting evidence has showed that Tumor-associated calcium signal transducer 2 (Trop2) is upregulated in various kinds of human cancers and plays important roles in tumorigenesis. However, the expression status and functional significance of Trop2 in thyroid cancer are largely unknown. METHODS: We first determined the expression of Trop2 by using RNAseqV2 data sets for thyroid cancer deposited on The...

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PMID: 28709407
DOI: 10.1186/s12885-017-3475-2

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