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TGF-β induces EMT in thyroid cancer cells by regulating transcription factors

9 Jun 2025

Abstract excerpt

BACKGROUND: Transforming growth factor-β (TGF-β) plays well-established roles in cancer cell invasion and epithelial-mesenchymal transition (EMT); however, its role in thyroid carcinoma (TC) remains unclear. This study aimed to evaluate the effects of TGF-β on EMT in TC and determine its underlying mechanisms. METHODS: Treatment of TC cell lines with TGF-β the morphology of thyroid cancer cells changed,...

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PMID: 40490818
DOI: 10.1186/s13044-025-00243-w

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