Article
Genetic diversity of variants involved in drug response and metabolism in Sri Lankan populations: implications for clinical implementation of pharmacogenomics.
Pharmacogenetics and genomics - 1 Jan 2016
Chan Sze Ling, Samaranayake Nilakshi, Ross Colin J D, Toh Meng Tiak, Carleton Bruce, Hayden Michael R, Teo Yik Ying, Dissanayake Vajira H W, Brunham Liam R
Abstract excerpt
BACKGROUND: Interpopulation differences in drug responses are well documented, and in some cases they correspond to differences in the frequency of associated genetic markers. Understanding the diversity of genetic markers associated with drug response across different global populations is essential to infer population rates of drug response or risk for adverse drug reactions, and to guide implementation of...
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