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Article

Genetic diversity of variants involved in drug response among Tunisian and Italian populations toward personalized medicine.

Scientific reports - 10 Mar 2024

Jmel Haifa, Sarno Stefania, Giuliani Cristina, Boukhalfa Wided, Abdelhak Sonia, Luiselli Donata, Kefi Rym

Abstract excerpt

Adverse drug reactions (ADR) represent a significant contributor to morbidity and mortality, imposing a substantial financial burden. Genetic ancestry plays a crucial role in drug response. The aim of this study is to characterize the genetic variability of selected pharmacogenes involved with ADR in Tunisians and Italians, with a comparative analysis against global populations. A cohort of 135 healthy Tunisians...

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Identifiers

PMID: 38462643
DOI: 10.1038/s41598-024-55239-7
PMCID: PMC10925599

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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