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Article

Pharmacogenetic landscape of Metabolic Syndrome components drug response in Tunisia and comparison with worldwide populations.

PloS one - 1 Jan 2018

Jmel Haifa, Romdhane Lilia, Ben Halima Yosra, Hechmi Meriem, Naouali Chokri, Dallali Hamza, Hamdi Yosr, Shan Jingxuan, Abid Abdelmajid, Jamoussi Henda, Trabelsi Sameh, Chouchane Lotfi, Luiselli Donata, Abdelhak Sonia, Kefi Rym

Abstract excerpt

Genetic variation is an important determinant affecting either drug response or susceptibility to adverse drug reactions. Several studies have highlighted the importance of ethnicity in influencing drug response variability that should be considered during drug development. Our objective is to characterize the genetic variability of some pharmacogenes involved in the response to drugs used for the treatment of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29652911
DOI: 10.1371/journal.pone.0194842
PMCID: PMC5898725

Genes

VIP
ABCB1
HMGCR
VKORC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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