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Article

Rtt107 Is a Multi-functional Scaffold Supporting Replication Progression with Partner SUMO and Ubiquitin Ligases.

Molecular cell - 15 Oct 2015

Hang Lisa E, Peng Jie, Tan Wei, Szakal Barnabas, Menolfi Demis, Sheng Ziwei, Lobachev Kirill, Branzei Dana, Feng Wenyi, Zhao Xiaolan

Abstract excerpt

Elucidating the individual and collaborative functions of genome maintenance factors is critical for understanding how genome duplication is achieved. Here, we investigate a conserved scaffold in budding yeast, Rtt107, and its three partners: a SUMO E3 complex, a ubiquitin E3 complex, and Slx4. Biochemical and genetic findings show that Rtt107 interacts separately with these partners and contributes to their...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Fungal

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Share to Intracellular Signaling Peptides and Proteins

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Source

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Identifiers

PMID: 26439300
DOI: 10.1016/j.molcel.2015.08.023
PMCID: PMC4609303

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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