Article
Contribution of BDNF and DRD2 genetic polymorphisms to continued opioid use in patients receiving methadone treatment for opioid use disorder: an observational study.
Addiction science & clinical practice - 6 Oct 2015
Bawor Monica, Dennis Brittany B, Tan Charlie, Pare Guillaume, Varenbut Michael, Daiter Jeff, Plater Carolyn, Worster Andrew, Marsh David C, Steiner Meir, Anglin Rebecca, Desai Dipika, Thabane Lehana, Samaan Zainab
Abstract excerpt
BACKGROUND: The heritability of opioid use disorder has been widely investigated; however, the influence of specific genes on methadone treatment outcomes is not well understood. The association between response to methadone treatment and genes that are involved in substance use behaviors and reward mechanisms is poorly understood, despite evidence suggesting their contribution to opioid use disorder. The aim of...
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