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Article

BDNF variability in opioid addicts and response to methadone treatment: preliminary findings.

Genes, brain, and behavior - 1 Jul 2008

de Cid R, Fonseca F, Gratacòs M, Gutierrez F, Martín-Santos R, Estivill X, Torrens M

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) signaling pathways have been shown to be essential for opioid-induced plasticity. We conducted an exploratory study to evaluate BDNF variability in opioid addict responders and nonresponders to methadone maintenance treatment (MMT). We analyzed 21 single nucleotide polymorphisms (SNPs) across the BDNF genomic region. Responders and nonresponders were classified by means of...

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Source

Identifiers

PMID: 18182069
DOI: 10.1111/j.1601-183X.2007.00386.x

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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