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Article

Association of dopamine and opioid receptor genetic polymorphisms with response to methadone maintenance treatment.

Progress in neuro-psychopharmacology & biological psychiatry - 1 Oct 2008

Crettol Séverine, Besson Jacques, Croquette-Krokar Marina, Hämmig Robert, Gothuey Isabelle, Monnat Martine, Déglon Jean-Jacques, Preisig Martin, Eap Chin B

Abstract excerpt

BACKGROUND: Genetic variations of the dopamine and opioid receptors could influence the response to methadone maintenance treatment (MMT). METHODS: We included 238 MMT patients according to their response to treatment and methadone dosing, along with 217 subjects without substance dependence. All were genotyped for polymorphisms of the dopamine D1, D2, micro-opioid and delta-opioid receptor genes. RESULTS: The...

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Source

Identifiers

PMID: 18687376
DOI: 10.1016/j.pnpbp.2008.07.009

Genes

DRD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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