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Article

Loss of the Drosophila melanogaster DEAD box protein Ddx1 leads to reduced size and aberrant gametogenesis.

Developmental biology - 15 Nov 2015

Germain Devon R, Li Lei, Hildebrandt Matthew R, Simmonds Andrew J, Hughes Sarah C, Godbout Roseline

Abstract excerpt

Mammalian DDX1 has been implicated in RNA trafficking, DNA double-strand break repair and RNA processing; however, little is known about its role during animal development. Here, we report phenotypes associated with a null Ddx1 (Ddx1(AX)) mutation generated in Drosophila melanogaster. Ddx1 null flies are viable but significantly smaller than control and Ddx1 heterozygous flies. Female Ddx1 null flies have reduced...

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Source

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Identifiers

PMID: 26433063
DOI: 10.1016/j.ydbio.2015.09.012
PMCID: PMC7094483

Genes

DDX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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