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Article

Combined Effects of GSTM1 Null Allele and APOL1 Renal Risk Alleles in CKD Progression in the African American Study of Kidney Disease and Hypertension Trial.

Journal of the American Society of Nephrology : JASN - 1 Oct 2016

Bodonyi-Kovacs Gabor, Ma Jennie Z, Chang Jamison, Lipkowitz Michael S, Kopp Jeffrey B, Winkler Cheryl Ann, Le Thu H

Abstract excerpt

Apolipoprotein L-1 (APOL1) high-risk alleles and the glutathione-S-transferase-μ1 (GSTM1) null allele have been shown separately to associate with CKD progression in the African American Study of Kidney Disease and Hypertension (AASK) trial participants. Here, we determined combined effects of GSTM1 null and APOL1 high-risk alleles on clinical outcomes in 682 AASK participants who were classified into four groups...

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Share to Apolipoprotein L1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lipoproteins, HDL

Share to Randomized Controlled Trials as Topic

Share to Renal Insufficiency, Chronic

Source

Open in PubMed Open full text

Identifiers

PMID: 26940095
DOI: 10.1681/ASN.2015050487
PMCID: PMC5042657

Genes

APOL1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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