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Article

GNL3 and SKA3 are novel prostate cancer metastasis susceptibility genes.

Clinical & experimental metastasis - 1 Dec 2015

Lee Minnkyong, Williams Kendra A, Hu Ying, Andreas Jonathan, Patel Shashank J, Zhang Suiyuan, Crawford Nigel P S

Abstract excerpt

Prostate cancer (PC) is very common in developed countries. However, the molecular determinants of PC metastasis are unclear. Previously, we reported that germline variation influences metastasis in the C57BL/6-Tg(TRAMP)8247Ng/J (TRAMP) mouse model of PC. These mice develop prostate tumors similar to a subset of poor outcome, treatment-associated human PC tumors. Here, we used TRAMP mice to nominate candidate...

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Source

Identifiers

PMID: 26429724
DOI: 10.1007/s10585-015-9745-y

Genes

GNL3
SKA3
ZMYM5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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