PTPRD gene associated with blood pressure response to atenolol and resistant hypertension.

doi:10.1097/HJH.0000000000000714

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Article

PTPRD gene associated with blood pressure response to atenolol and resistant hypertension.

Journal of hypertension - 1 Nov 2015

Gong Yan, McDonough Caitrin W, Beitelshees Amber L, El Rouby Nihal, Hiltunen Timo P, O'Connell Jeffrey R, Padmanabhan Sandosh, Langaee Taimour Y, Hall Karen, Schmidt Siegfried O F, Curry Robert W, Gums John G, Donner Kati M, Kontula Kimmo K, Bailey Kent R, Boerwinkle Eric, Takahashi Atsushi, Tanaka Toshihiro, Kubo Michiaki, Chapman Arlene B, Turner Stephen T, Pepine Carl J, Cooper-DeHoff Rhonda M, Johnson Julie A

Abstract excerpt

OBJECTIVE: The aim of this study is to identify single-nucleotide polymorphisms (SNPs) influencing blood pressure (BP) response to the β-blocker atenolol. METHODS: Genome-wide association analysis of BP response to atenolol monotherapy was performed in 233 white participants with uncomplicated hypertension in the pharmacogenomic evaluation of antihypertensive responses study. Forty-two polymorphisms with P less...

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Identifiers

PMID: 26425837
DOI: 10.1097/HJH.0000000000000714
PMCID: PMC4788379

Genes

PTPRD
DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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