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Article

Increased frequency of co-existing JAK2 exon-12 or MPL exon-10 mutations in patients with low JAK2(V617F) allelic burden.

Leukemia & lymphoma - 1 Jan 2016

Nussenzveig Roberto H, Pham Ha T, Perkins Sherrie L, Prchal Josef T, Agarwal Archana M, Salama Mohamed E

Abstract excerpt

The frequency of co-existing JAK2(V617F)/MPL and JAK2(V617F)/JAK2 exon-12 mutations has not been previously investigated in MPNs. Poor survival was reported in primary myelofibrosis with low JAK2(V617F) allelic burden. However, mutational status of JAK2 exon-12 or MPL were not reported in these patients. This study developed a cost-effective multiplex high resolution melt assay that screens for mutations in JAK2...

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Source

Identifiers

PMID: 26419289
DOI: 10.3109/10428194.2015.1091932

Genes

JAK2
MPL

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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