Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[JAK2 V617F mutation burden and its clinical implications in 415 patients with myeloproliferative neoplasm].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Mar 2015

Liu Yuquan, Liu Chuanfang, He Na, Wang Min, Zhang Xinxiu, Tang Dongyi, Ji Chunyan, Ma Daoxin

Abstract excerpt

OBJECTIVE: To detect JAK2 V617F mutation burden and its clinical implications in patients with myeloproliferative neoplasm (MPN). METHODS: JAK2 V617F mutation burden were detected by using MGB Taqman probes and its clinical significance were retrospectively studied in 415 MPN patients. RESULTS: JAK2 V617F was found in 56.9% of all patients [83.5% in polycythemia vera (PV), 55.9% in essential thrombocythemia (ET),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Homozygote
Share to Janus Kinase 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukocyte Count

Share to Mutation

Share to Myeloproliferative Disorders

Share to Platelet Count

Share to Polycythemia Vera

Share to Thrombocythemia, Essential

Source

Open in PubMed Open full text

Identifiers

PMID: 25854460
DOI: 10.3760/cma.j.issn.0253-2727.2015.03.004
PMCID: PMC7342523

Genes

JAK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[JAK2 V617F mutation burden and its clinical implications in 415 patients with myeloproliferative neoplasm].PMID 25854460Read ↗

Study on the Clinical Significance of JAK2V617F Allele Burden in Philadelphia Chromosome-Negative Myeloproliferative Neoplasm.Semantic proximity Read ↗

[Clinical study on relationship between JAK2 V617F mutation and chronic myeloproliferative disorders].Semantic proximity Read ↗

[Detection and clinical significance of JAK2 mutation in 412 patients with chronic myeloproliferative neoplasms].Semantic proximity Read ↗

[Clinical significance of the quantification of JAK2V617F allele burden in classical Ph-negative myeloproliferative neoplasms].Semantic proximity Read ↗

JAK2 V617F Mutational Burden and Clinical Findings Relationship in Myeloproliferative NeoplasmsSemantic proximity Read ↗

[JAK2V617F mutation in the patients with myeloproliferative disorder and its relation with clinical characteristics].Semantic proximity Read ↗

High Risk Janus Kinase 2 V617F Allele Burden in a Seven-Year Cohort of Patients with Myeloproliferative Neoplasms.Semantic proximity Read ↗

JAK2V617F allele burden in patients with myeloproliferative neoplasms.Semantic proximity Read ↗

[A novel quantitative JAK2V617F detection kit: prospective clinical performance study comparing MPN patients and healthy subjects].Semantic proximity Read ↗

[The investigation of JAK2 V617F point mutation in myeloproliferative disorders by allele-specific polymerase chain reaction in combination with sequence analysis].Semantic proximity Read ↗

The JAK2 V617F allele burden in essential thrombocythemia, polycythemia vera and primary myelofibrosis--impact on disease phenotype.Semantic proximity Read ↗

[The genetic characteristics of BCR-ABL-negative myeloproliferative neoplasms].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.