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Article

MPL mutation profile in JAK2 mutation-negative patients with myeloproliferative disorders.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Mar 2011

Ma Wanlong, Zhang Xi, Wang Xiuqiang, Zhang Zhong, Yeh Chen-Hsiung, Uyeji Jennifer, Albitar Maher

Abstract excerpt

Mutations in the thrombopoietin receptor gene (myeloproliferative leukemia, MPL) have been reported in patients with JAK2 V617F-negative chronic myeloproliferative disorders (MPDs). We evaluated the prevalence of MPL mutations relative to JAK2 mutations in patients with suspected MPDs. A total of 2790 patient samples submitted for JAK2 mutation analysis were tested using real-time polymerase chain reaction and...

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Source

Identifiers

PMID: 21326037
DOI: 10.1097/PDM.0b013e3181ecd261

Genes

JAK2
MPL

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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