Laboratory practice guidelines for detecting and reporting JAK2 and MPL mutations in myeloproliferative neoplasms: a report of the Association for Molecular Pathology.

doi:10.1016/j.jmoldx.2013.07.002

Article

Laboratory practice guidelines for detecting and reporting JAK2 and MPL mutations in myeloproliferative neoplasms: a report of the Association for Molecular Pathology.

The Journal of molecular diagnostics : JMD - 1 Nov 2013

Gong Jerald Z, Cook James R, Greiner Timothy C, Hedvat Cyrus, Hill Charles E, Lim Megan S, Longtine Janina A, Sabath Daniel, Wang Y Lynn

Abstract excerpt

Recurrent mutations in JAK2 and MPL genes are genetic hallmarks of BCR-ABL1-negative myeloproliferative neoplasms. Detection of JAK2 and MPL mutations has been incorporated into routine diagnostic algorithms for these diseases. This Special Article summarizes results from a nationwide laboratory survey of JAK2 and MPL mutation analysis. Based on the current practice pattern and the literature, this Special...

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Laboratory practice guidelines for detecting and reporting JAK2 and MPL mutations in myeloproliferative neoplasms: a report of the Association for Molecular Pathology.

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