Article
Association of prostate cancer risk variants with clinicopathologic characteristics of the disease.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Sept 2008
Xu Jianfeng, Isaacs Sarah D, Sun Jielin, Li Ge, Wiley Kathleen E, Zhu Yi, Hsu Fang-Chi, Wiklund Fredrik, Turner Aubrey R, Adams Tamara S, Liu Wennuan, Trock Bruce J, Partin Alan W, Chang Baoli, Walsh Patrick C, Grönberg Henrik, Isaacs William, Zheng Siqun
Abstract excerpt
PURPOSE: Fifteen independent genetic variants have been implicated in prostate cancer risk by recent genome-wide association studies. However, their association with clinicopathologic features of prostate cancer is uncertain. EXPERIMENTAL DESIGN: We systematically evaluated these 15 variants in 1,563 prostate cancer patients undergoing radical prostatectomy, taking advantage of the uniform tumor stage and grade...
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