Article
Prostate cancer susceptibility variants confer increased risk of disease progression.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 2010
Cheng Iona, Plummer Sarah J, Neslund-Dudas Christine, Klein Eric A, Casey Graham, Rybicki Benjamin A, Witte John S
Abstract excerpt
BACKGROUND: Genome-wide association studies have identified numerous single nucleotide polymorphisms (SNP) associated with the risk of prostate cancer. Our objective was to determine whether these SNPs affect the progression of prostate cancer. METHODS: We genotyped 26 SNPs previously associated with prostate cancer risk among 788 aggressive prostate cancer patients who were treated by radical prostatectomy or...
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