Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An initial investigation of associations between dopamine-linked genetic variation and smoking motives in African Americans.

Pharmacology, biochemistry, and behavior - 1 Nov 2015

Bidwell L C, McGeary J E, Gray J C, Palmer R H C, Knopik V S, MacKillop J

Abstract excerpt

Nicotine dependence (ND) is a heterogeneous phenotype with complex genetic influences that may vary across ethnicities. The use of intermediate phenotypes may clarify genetic influences and reveal specific etiological pathways. Prior work in European Americans has found that the four Primary Dependence Motives (PDM) subscales (Automaticity, Craving, Loss of Control, and Tolerance) of the Wisconsin Inventory of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black or African American
Share to Dopamine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Tolerance

Share to Motivation

Share to Neuropsychological Tests

Share to Smoking

Share to United States

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 26410615
DOI: 10.1016/j.pbb.2015.09.018
PMCID: PMC4635661

Genes

DBH
DRD2
NCAM1
COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An initial investigation of associations between dopamine-linked genetic variation and smoking motives in African Americans.PMID 26410615Read ↗

NCAM1-TTC12-ANKK1-DRD2 variants and smoking motives as intermediate phenotypes for nicotine dependence.Semantic proximity Read ↗

Refining the tobacco dependence phenotype using the Wisconsin Inventory of Smoking Dependence Motives.Semantic proximity Read ↗

Haplotype spanning TTC12 and ANKK1, flanked by the DRD2 and NCAM1 loci, is strongly associated to nicotine dependence in two distinct American populations.Semantic proximity Read ↗

Dissection of the phenotypic and genotypic associations with nicotinic dependence.Semantic proximity Read ↗

Genome-wide single nucleotide polymorphism heritability of nicotine dependence as a multidimensional phenotype.Semantic proximity Read ↗

Genetic variants and early cigarette smoking and nicotine dependence phenotypes in adolescents.Semantic proximity Read ↗

Phenotypic and genetic factors in motives for smoking.Semantic proximity Read ↗

Bitter taste receptor gene polymorphisms are an important factor in the development of nicotine dependence in African Americans.Semantic proximity Read ↗

Genetic and Epigenetic Analysis Revealing Variants in the NCAM1-TTC12-ANKK1-DRD2 Cluster Associated Significantly With Nicotine Dependence in Chinese Han Smokers.Semantic proximity Read ↗

Significant associations of CHRNA2 and CHRNA6 with nicotine dependence in European American and African American populations.Semantic proximity Read ↗

Haplotypic variants in DRD2, ANKK1, TTC12, and NCAM1 are associated with comorbid alcohol and drug dependence.Semantic proximity Read ↗

The relationship between rs3779084 in the dopa decarboxylase (DDC) gene and alcohol consumption is mediated by drinking motives in regular smokers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.