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Article

Bitter taste receptor gene polymorphisms are an important factor in the development of nicotine dependence in African Americans.

Journal of medical genetics - 1 Sept 2008

Mangold J E, Payne T J, Ma J Z, Chen G, Li M D

Abstract excerpt

CONTEXT: Bitter sensitivity varies among individuals and ethnic groups partly due to polymorphisms in taste receptor genes (TAS2Rs). Although previous psychophysical studies suggest that taste status plays a role in nicotine dependence (ND), genetic evidence is lacking. OBJECTIVES: To determine whether single nucleotide polymorphisms (SNPs) in TAS2R16 and TAS2R38 are associated with ND and if the effects differ...

Topics

Adult
Black or African American
Female
Haplotypes
Humans
Male
Polymorphism, Single Nucleotide
Receptors, G-Protein-Coupled
Sex Factors
Tobacco Use Disorder
Taste Receptors, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18524836
DOI: 10.1136/jmg.2008.057844

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-18524836-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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