Article
Bitter taste receptor gene polymorphisms are an important factor in the development of nicotine dependence in African Americans.
Journal of medical genetics - 1 Sept 2008
Mangold J E, Payne T J, Ma J Z, Chen G, Li M D
Abstract excerpt
CONTEXT: Bitter sensitivity varies among individuals and ethnic groups partly due to polymorphisms in taste receptor genes (TAS2Rs). Although previous psychophysical studies suggest that taste status plays a role in nicotine dependence (ND), genetic evidence is lacking. OBJECTIVES: To determine whether single nucleotide polymorphisms (SNPs) in TAS2R16 and TAS2R38 are associated with ND and if the effects differ...
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