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Article

Genetic variants and early cigarette smoking and nicotine dependence phenotypes in adolescents.

PloS one - 1 Jan 2014

O'Loughlin Jennifer, Sylvestre Marie-Pierre, Labbe Aurélie, Low Nancy C, Roy-Gagnon Marie-Hélène, Dugas Erika N, Karp Igor, Engert James C

Abstract excerpt

BACKGROUND: While the heritability of cigarette smoking and nicotine dependence (ND) is well-documented, the contribution of specific genetic variants to specific phenotypes has not been closely examined. The objectives of this study were to test the associations between 321 tagging single-nucleotide polymorphisms (SNPs) that capture common genetic variation in 24 genes, and early smoking and ND phenotypes in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25545355
DOI: 10.1371/journal.pone.0115716
PMCID: PMC4278712

Genes

OPRM1
COMT
DDC
DRD2
CHRNA7
IMPACT

Provenance

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