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Article

Bone marrow microenvironment modulation of acute lymphoblastic leukemia phenotype.

Experimental hematology - 1 Jan 2016

Moses Blake S, Slone William L, Thomas Patrick, Evans Rebecca, Piktel Debbie, Angel Peggi M, Walsh Callee M, Cantrell Pamela S, Rellick Stephanie L, Martin Karen H, Simpkins James W, Gibson Laura F

Abstract excerpt

Acute lymphoblastic leukemia (ALL) treatment regimens have dramatically improved the survival of ALL patients. However, chemoresistant minimal residual disease that persists following cessation of therapy contributes to aggressive relapse. The bone marrow microenvironment (BMM) is an established "site of sanctuary" for ALL, as well as myeloid-lineage hematopoietic disease, with signals in this unique anatomic...

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Identifiers

PMID: 26407636
DOI: 10.1016/j.exphem.2015.09.003
PMCID: PMC4684957

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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