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Article

The bone marrow microenvironment in health and disease at a glance

15 Feb 2018

Abstract excerpt

The bone marrow microenvironment (BMM) is the 'domicile' of hematopoietic stem cells, as well as of malignant processes that can develop there. Multiple and complex interactions with the BMM influence hematopoietic stem cell (HSC) physiology, but also the pathophysiology of hematological malignancies. Reciprocally, hematological malignancies alter the BMM, in order to render it more hospitable for malignant...

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PMID: 29472498
DOI: 10.1242/jcs.201707

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