Article

Patient-Derived Intrafemoral Orthotopic Xenografts of Peripheral Blood or Bone Marrow from Acute Myeloid and Acute Lymphoblastic Leukemia Patients: Clinical Characterization, Methodology, and Validation

2022-03-16

Abstract excerpt

Acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) are malignant clonal diseases of the hematopoietic system with an unsatisfactory overall prognosis. The main obstacle is the increased resistance of AML and ALL cells to chemotherapy. The development and validation of new therapeutic strategies for acute leukemia require preclinical models that accurately recapitulate the genetic, pathological, an...

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Literature Corpus work: cec53acd-578d-59c7-8816-d220f81b148a
DOI: 10.21203/rs.3.rs-1444342/v1

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Patient-Derived Intrafemoral Orthotopic Xenografts of Peripheral Blood or Bone Marrow from Acute Myeloid and Acute Lymphoblastic Leukemia Patients: Clinical Characterization, Methodology, and ValidationDOI 10.21203/rs.3.rs-1444342/v1Read

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