To Study the Association of HLA-DQ2/8 With Celiac Disease and Identifying Proxy-SNPs for Predicting Their Presence in North Indian Population.

Abstract excerpt

Celiac disease (CD) risk conferred by HLA-DQ2 and DQ8 varies significantly across populations. In north India, where CD is as prevalent as in European populations, reports on the association of HLA-DQ2 and DQ8 with CD are limited. In a north Indian CD case-control cohort (459 CD and 450 controls), known CD-associated risk HLA-DQ alleles, HLA-DQA1*05:01/02:01/03:01 and HLA-DQB1*02/*03:02, were genotyped using...

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• Case-Control Studies
• Celiac Disease
• Child, Preschool
• Gene Frequency
• Genetic Association Studies