Article
High allele frequency of CYP2C9*3 (rs1057910) in a Negrito's subtribe population in Malaysia; Aboriginal people of Jahai.
Annals of human biology - 1 Sept 2016
Rosdi Rasmaizatul Akma, Mohd Yusoff Narazah, Ismail Rusli, Soo Choon Tan, Saleem Mohamed, Musa Nurfadhlina, Yusoff Surini
Abstract excerpt
BACKGROUND: CYP2C9 gene polymorphisms modulate inter-individual variations in the human body's responses to various endogenous and exogenous drug substrates. To date, little is known about the CYP2C9 gene polymorphisms among the aboriginal populations of the world, including those in Malaysia. AIM: To characterise and compare the CYP2C9 polymorphisms (CYP2C9*2, CYP2C9*3, CYP2C9*4 and CYP2C9*5) between one of...
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