Article
CYP2C9 polymorphism: prevalence in healthy and warfarin-treated Malay and Chinese in Malaysia.
Singapore medical journal - 1 May 2009
Ngow H A, Wan Khairina W M, Teh L K, Lee W L, Harun R, Ismail R, Salleh M Z
Abstract excerpt
INTRODUCTION: Genetic polymorphisms of CYP2C9 among different populations in different geographical regions could be different. CYP2C9 has been reported to be the enzyme responsible for the metabolism of many drugs, including warfarin and other drugs with a narrow therapeutic index. Realising the importance of inter-individual differences in the genetic profile in determining the outcome of a drug therapy, this...
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