Significant genotype difference in the CYP2E1 PstI polymorphism of indigenous groups in Sabah, Malaysia with Asian and non-Asian populations.

Abstract excerpt

CYP2E1 PstI polymorphism G-1259C (rs3813867) genotype distributions vary significantly among different populations and are associated with both diseases, like cancer, and adverse drug effects. To date, there have been limited genotype distributions and allele frequencies of this polymorphism reported in the three major indigenous ethnic groups (KadazanDusun, Bajau, and Rungus) in Sabah, also known as North...

Topics

• Adolescent
• Adult
• Aged
• Aged, 80 and over
• Asian People
• Cytochrome P-450 CYP2E1
• Electrophoresis, Agar Gel
• Female
• Gene Frequency
• Genotype
• Healthy Volunteers