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Article

TGF-β1 Codon 10 T>C Polymorphism Influences Short-Term Functional and Cognitive Decline in Healthy Oldest-Old Individuals: The Pietà Study.

Journal of Alzheimer's disease : JAD - 1 Jan 2015

Fraga Vanessa G, Guimarães Henrique C, Lara Vivian P, Teixeira Antônio L, Barbosa Maira T, Carvalho Maria G, Caramelli Paulo, Gomes Karina B

Abstract excerpt

BACKGROUND: Inflammation and cytokine production are a common finding in aging, which probably exert influence on cognitive and functional abilities in elderly people. Transforming-growth-factor beta 1 (TGF-β1) is an important multifunctional anti-inflammatory cytokine that displays immunomodulatory activities. OBJECTIVE: This prospective investigation aimed to evaluate the TGF-β1 codon 10 T>C on functional and...

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Source

Identifiers

PMID: 26402106
DOI: 10.3233/JAD-150397

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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